Turning his final presidential debate appearance into an unprecedented assault on US political convention, Donald Trump refused on Wednesday to say that he would respect a Hillary Clinton victory in November.

One of the most powerful typhoons to ever hit the Philippines destroyed houses, tore roofs off schools and ripped giant trees out of the ground today, but there were no immediate reports of deaths.

The UN General Assembly will discuss the worsening violence in Syria today after the Security Council failed to take action to end the bombing raids on Aleppo and revive peace efforts.

British Prime Minister Theresa May will seek to allay fears of the disruptive impact of Brexit after a wave of criticism when she addresses European Union leaders today at her first EU summit.

Scientists reported on Wednesday the first evidence that the immune systems of wild Tasmanian devils can fight back against the contagious face cancer that has pushed the species to the brink of extinction.

The UN Security Council agreed on Tuesday that a new UN mission for Colombia could continue to monitor a ceasefire despite a referendum vote rejecting the peace deal.

Venezuela on Tuesday postponed gubernatorial elections due in December until mid-2017 after deeply unpopular President Nicolas Maduro said the country needs to focus on reviving its economy instead of elections.

French Interior Minister Bernard Cazeneuve said on Tuesday the demolition of the "Jungle" migrant camp in Calais would take place "within days" after a court rejected a last-ditch bid by charities to block it.

Russia on Monday announced an eight-hour "humanitarian" ceasefire in Aleppo later this week, as the EU warned that the Syrian regime's Moscow-backed assault on the city could amount to war crimes.