|Medical workers prepare the COVID-19 vaccine doses to inject into the volunteers. Photo: vietnamplus.vn|
HÀ NỘI — Three volunteers who received a 25mcg dose of Nanocovax – the first Vietnamese COVID-19 vaccine to be tested on humans – last December received their second shot yesterday.
The three, comprising one male and two females aged between 20 and 25, are among the first 20 volunteers given the vaccine on December 17, 2020.
Professor Đỗ Quyết, Director of the Hà Nội-based Việt Nam Military Medical University, said the second shot comes 28 days after the first one.
As volunteers haven’t shown abnormal symptoms after getting the first injection, the 25mcg, 50mcg, and 75mcg doses of Nanocovax have been tested on the remaining groups of volunteers safely.
So far, all volunteers have been in stable health conditions. Some felt pain at the injection site or mild fever, but the symptoms disappeared after 24 hours, Quyết noted.
Associate Professor Chử Văn Mến, director of the university’s clinical trial centre, said 50 per cent of the first phase of human trials has completed.
The university has received more than 500 applications for Nanocovax trials, but only 51 were eligible for the first phase of testing due to strict selection criteria.
Phase I, with doses of 25mcg, 50mcg, and 75mcg, aims to evaluate the vaccine’s safety. Phase II is set to conduct testing on 560 people and begin in February to assess the vaccine’s effectiveness. Meanwhile, the third phase will need at least 1,500 - 3,000 volunteers, including those in other countries.
If everything goes as planned, the first two phases will finish in February and be followed by the third one when half of Phase II is completed.
Việt Nam is one of the 40 countries that have conducted human trials of a COVID-19 vaccine.
Nanocovax is developed by the Nanogen Pharmaceutical Biotechnology JSC, basing on recombinant protein technology.
The country also has several other COVID-19 candidate vaccines being developed, by the Institute of Vaccines and Medical Biologicals (IVAC), the Company for Vaccine and Biological Production No.1 (VABIOTECH), and the Centre for Research and Production of Vaccines and Biologicals (POLYVAC). — VNS